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IRINOTEL 100MG INJECTION contains Irinotecan which belongs to the group of medicines called Anticancer agents. It is used to treat advanced or metastatic colorectal cancer (cancers of colon and rectum). It can also be used to treat colorectal cancer among patients whose disease has recurred or progressed following initial chemotherapy with 5-Fluorouracil.

IRINOTEL 100MG INJECTION is mostly used in combination with other anticancer medicines to achieve better results. Before receiving IRINOTEL 100MG INJECTION inform your doctor if you have hypertension or any other heart problems.

You must also inform your doctor if you have high blood cholesterol levels, elevated bilirubin levels in the blood or any inflammation in the gut as a precaution. IRINOTEL 100MG INJECTION is not recommended for use in pregnant or breastfeeding women as it may harm the growing baby.

Both men and women of childbearing potential must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with this medicine. Men may seek advice on sperm preservation, if necessary, prior to the therapy with this medicine.

IRINOTEL 100MG INJECTION may cause severe nausea, vomiting and diarrhea. To manage this, your doctor will prescribe a suitable anti-emetic and antidiarrheal medicines along with this medicine. However, inform your doctor immediately if these side effects worsen.

Other most common side effects of receiving IRINOTEL 100MG INJECTION are stomach pain mouth ulcers, hair loss, tiredness, weakness, increased infections, increased bleeding tendency and difficulty in passing stools. Consult your doctor if any of these side effects trouble you.

Active Ingredient (Generic Name):Irinotecan
Indication:Ovarian cancer, Small cell lung cancer, Cervical cancer
Manufacturer:Fresenius Kabi India Pvt.Ltd.
Packaging:5 ml in 1 vial
Strength:100mg+5ml
Delivery Time:6 To 15 days

 

USES OF IRINOTEL 100MG INJECTION

  • Treats advanced or metastatic cancers of colon or rectum

 

HOW IRINOTEL 100MG INJECTION WORKS

IRINOTEL 100MG INJECTION is an anticancer medication. It works by blocking the actions of certain enzymes (DNA-Topoisomerase-1) within the cells which is required for the cells to grow and multiply. As a result, it prevents abnormal cell division and slows down the growth and spread of cancer cells within the body.

 

DIRECTIONS FOR USE

IRINOTEL 100MG INJECTION will be given to you only by a doctor or a nurse into the vein (as an intravenous infusion).

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

 

SIDE EFFECTS OF IRINOTEL 100MG INJECTION

COMMON

  • Low RBC count causing anemia, tiredness and pale skin
  • Increased infections
  • Loss of appetite
  • Hair loss
  • Nausea, vomiting, stomach pain
  • Mouth ulcers
  • Tiredness, weakness
  • Increased bleeding tendency due to low blood platelet counts
  • Difficulty in passing stools

Contact your doctor immediately if you experience any of the following side effects after receiving IRINOTEL 100MG INJECTION:

  • Severe infections causing fever due to low WBC count in blood
  • Severe diarrhoea, vomiting or nausea
  • Signs of acute cholinergic syndrome (such as runny nose, increased saliva, excess tears in the eyes, sweating, flushing, stomach cramps and diarrhoea)
  • Signs of lung problems (such as new or worsening cough, trouble breathing, and fever)
  • Signs of blood clot formation in the body (such as chest pain, shortness of breath, or swelling, pain, redness, or warmth in an arm or leg)
  • Severe stomach pain with bloating and difficulty in passing stools
  • Severe pain, redness and swelling at the injection site

 

 

HOW TO MANAGE SIDE EFFECTS

Mouth Ulcers

Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve.

Nausea And Vomiting

Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the symptoms are worsening.

 

WARNING & PRECAUTIONS

PREGNANCY

CONTRAINDICATED

IRINOTEL 100MG INJECTION is not recommended for use in pregnant women as it may cause harm to the growing baby. Therefore, inform your doctor before receiving it. Women of childbearing potential must use a suitable contraceptive method to avoid pregnancy during the treatment and for at least 6 months after the last dose.

BREASTFEEDING

CONTRAINDICATED

IRINOTEL 100MG INJECTION is not recommended for use in women who are breastfeeding. Therefore, consult your doctor before receiving it.

DRIVING AND USING MACHINES

USE WITH CAUTION

IRINOTEL 100MG INJECTION may cause dizziness and vision problem during the first 24 hours after receiving it. Therefore, do not drive or handle any heavy tools or machines if your ability is affected by this medicine.

ALLERGY

CONTRAINDICATED

Talk to your doctor before receiving IRINOTEL 100MG INJECTION if you are allergic to Irinotecan.

HEART DISEASE

USE WITH CAUTION

IRINOTEL 100MG INJECTION should be used with caution in patients with hypertension or any other heart diseases. Therefore, inform your doctor before receiving it.

USE IN PEDIATRICS

CONSULT YOUR DOCTOR

The safety and efficacy of IRINOTEL 100MG INJECTION have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor before receiving it.

USE IN GERIATRICS

USE WITH CAUTION

IRINOTEL 100MG INJECTION should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before receiving it.

OTHERS

IRINOTEL 100MG INJECTION is not recommended for use if you:

  • Have any inflammation in the bowel for a prolonged period
  • Have any obstructions or block in the gut
  • Have elevated bilirubin levels in the blood
  • Have severe bone marrow failure
  • Are in a poor general condition
  • Are taking an herbal medicine called St. John’s Wort for mental illnesses
  • Recently got vaccinated with a live attenuated vaccine (Ex. vaccine for chicken pox, shingles, measles, mumps, rubella, tuberculosis, rotavirus, influenza)

Inform your doctor, before receiving IRINOTEL 100MG INJECTION, if you:

  • Have Gilbert’s syndrome (an inherited condition that causes elevated bilirubin levels and jaundice)
  • Have a habit of smoking
  • Have high blood cholesterol levels
  • Are scheduled for any surgeries (including minor dental surgeries)

Irinotel Injection

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